How do you clean a Primo water dispenser with vinegar?

How to Clean a Water Cooler With Vinegar Unplug the water cooler and remove the old, empty bottle. Add the water and vinegar to the bucket. Pour the vinegar into the reservoir of the water cooler. Let the vinegar sit for 10 to 15 minutes. Hold the bucket under both of the cold and hot taps on the water cooler.